3D DNA-PAINT image of the nuclear lamina protein Lamin A/C in a fixed CV-1 cell. Nuclear invagination is clearly observed in the 3D image captured with N-STORM.
Image depth: 5.1μm, Step size: 100nm
3D STORM imaging of actin labeled with Alexa Fluor® 647 Phalloidin using depth-code pseudo color. Image “a” shows four types of actin organization, from bottom left to top right: the cell body of a neuron, a glial cell with stress fibers, a neuronal dendrite with spines, and an axon.
Photos courtesy of: Dr. Christophe Leterrier, NeuroCyto team, NICN CNRS-AMU UMR7259, Marseille, France
3D-Stack STORM image of an African green monkey kidney cell (BSC-1) labeled with Alexa Fluor® 647（Mitochondria）. The image on the right is an enlargement and a movie of the area indicated by the arrow in the image on the left. Image depth: approx. 2μm
Mouse brain section (hippocampus CA1 region) immunostained against CB1 cannabinoid receptors using Alexa Fluor® 647.
With STORM imaging, the membrane of axon terminals with hollow are much sharply observed.
Photos courtesy of ; Barna Dudok Ph.D., Laszlo Barna Ph.D., Istvan Katona Ph.D., Laboratory of Molecular Neurobiology, Institute of Experimental Medicine of the Hungarian Academy of Sciences