The GaAsP NDD is equipped with GaAsP PMT that has a higher signal-to-noise ratio and superior sensitivity than a Multi-Alkali PMT, and allows clear imaging of deeper areas of living specimens. Its ability to acquire images of high S/N ratio, enables faster imaging and higher quality Z-stack imaging. Its high sensitivity allows the acquisition of fluorescent signals with less laser power, resulting in less photo damage to living specimens.
The Nikon A1 MP+ and A1R MP+ can be configured with a wavelength of 1080 nm, as well as a wavelength of 1300 nm that enables deep imaging up to 1.4 mm.
The NDDs are located as close as possible to the specimen in order to detect the maximum amount of scattered emission signals from deep within living specimens. A combination of episcopic and diascopic GaAsP NDDs for the Ni-E/FN1 upright microscope allows acquisition of bright and high S/N ratio images, by detecting both reflected and transmitted fluorescence signals.
Deep brain imaging in in vivo mouse with the GaAsP NDD compatible with the 1300 nm wavelength